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Notably, in vitro experiments revealed that inhibition of either PI3K or AKT negated the beneficial effects of berberine on IR, underscoring the pivotal role of the PI3K/AKT pathway in its mechanism of action (Yu et al., 2021)
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[DOI] [PMC free article] [PubMed] [Google Scholar] 46.Xia W., Tang N., Kord-Varkaneh H., Low T.Y., Tan S.C., Wu X., Zhu Y
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